Chapter 8 Links
Gene Therapy

Gene Therapy

• Genetic Testing and Gene Therapy
  • This will help you learn more about what gene testing and gene therapy could mean to you and your family. Many people, including those planning a pregnancy, are taking steps to learn more about their own genetic status. A service of NOAH (New York Online Access to Health), a Spanish/English repository of very useful health info. Chock full of great stuff!
• Questions and Answers About Gene Therapy
  • A good background on gene therapy from NIH.
• Gene Therapy of Cancer: November 1995
  • A report from CancerWeb discussing the use of gene therapy for treatment of cancer.
• University of North Carolina Human Gene Therapy Center
  • Provides the public and the scientific community with an opportunity to learn more about gene therapy research and work being pursued at our center; and to provide molecular biologists and virologists with convenient access to data gathered by our researchers and helpful links to scientific web resources. Fairly high level.
• The Institute for Human Gene Therapy
  • Follow the Clinical Trials links.
• Pittsburgh Human Gene Therapy Center
  • Take a look at their research programs.
• Pioneer James Wilson Reflects On Gene Therapy's Hopes, Hype
  • A question and answer session.

Retroviruses

• Retroviruses
  • This excellent site discusses everything you want to know about retroviruses - that includes taxonomy, structure, genome, reverse transcription, gene expression, and pathogenesis. The great plus of this site are numerous colorful diagrams and an activity where you can pretend to be a retrovirus.
• Retroviruses: An Introduction
  • A historical perspective of retroviruses.
• Retrovirus Replication
  • Here is a neat diagram from Access Excellence.
• Human Retrovirus Section
  • The Human Retrovirus Section of the National Cancer Institute performs basic research on the molecular biology of gene expression, on the biology of human retroviruses and the pathogenesis of AIDS. Very research oriented material.

Cystic Fibrosis

• Cystic Fibrosis
  • This is a good introduction to Cystic Fibrosis. It includes a definition, and information on frequency, symptoms, physical appearance, treatment, and prognosis.
• CF Web
  • This site has a lot of information on many aspects of CF. Some apects included are support groups, newspaper articles and books about people with CF, CF Information for the Non-Technical Reader, and CF Information for Doctors and Researchers.
• Cystic Fibrosis Foundation
  • The mission of the Cystic Fibrosis Foundation (CFF) is to assure the development of the means to cure and control cystic fibrosis (CF) and to improve the quality of life for those with the disease.
• A Family Guide to Cystic Fibrosis Genetic Testing
  • This is a very nice, easy to understand site. It answers questions such as: What is your chance of being a CF carrier? and Who will benefit from CF genetic testing?
• Pulmozyme DNase Approved for Treatment of Cystic Fibrosis
  • An article from the Feb. 94 issue of Medical Sciences Bulletin on this new CF drug.
    Also check out the Pulmozyme page at Genentech for more info.

Hypercholesterolemia

• Hypercholesterolemia Info. by Michael D. Myers, M.D.
  • Q & A about hypercholesterolemia.

AIDS and HIV

• The Body: A Multimedia AIDS and HIV Information Resource
  • A great looking site with a lot of information. The Body provides you with basic AIDS information, information on political issues, insight from experts, and opportunities for interaction. Highly recommended!
• HIV InSite
  • HIV InSite is designed as a gateway to in-depth information about particular aspects of HIV/AIDS.
• JAMA HIV/AIDS Information Center
  • An easy-to-use, interactive collection of useful and high-quality resources for physicians, other health professionals and the public. The links will let you access clinical updates, news, and information on a broad range of social and policy questions relating to HIV/AIDS.
• Ask NOAH About: AIDS and HIV
  • A great site full of a variety of information.
• Doctor's Guide to AIDS Information and Resources
  • This guide provides extensive links to medical news and alerts, disease and drug information, and links to discussion groups, newsgroups, and other sites. Go here to learn about new developments.

Sickle Cell Anemia

• Sickle Cell Disease
  • Very accessible and interesting information for the general public from the terrific resources of the New York Online Access to Health (NOAH) site.
• Sickle Cell Disease: Beyond The Pain, A Comprehensive Approach To Care
  • In-depth coverage of the disease and therapy issues from the Topics in Primary Care series at the U of Chicago's University Health Service.
• Sickle Cell Anemia
  • Excellent, indepth site!
• Sickle Cell Anemia
  • Another indepth site, but the focus here is on children.
• FAQ (Frequently Asked Questions) About Sickle Cell Anemia
  • Answers almost all questions including issues related to work.
• Sickle-Cell Patients Seek Respect
  • Because of the frequency of patients' crises and problems with physical dependency, hospital staff members have been known to stereotype individuals with sickle-cell disease.

  New Drug Treatment

• Clinical Alert: Drug Treatment for Sickle Cell Anemia
• First Treatment for Sickle Cell Anemia
• New Hope for People with Sickle Cell Anemia

Lesch Nyhan

• Lesch-Nyhan Disease
  • A good general introduction.
• Lesch Nyhan
  • A technical overview of this puzzling disorder from the Online Mendelian Inheritance in Man (OMIM) database.

Hemophilia

• Hemophilia Homepage
  • A great site with a lot of information.
• Hemophilia - A Genetic Disease
  • In this web page, we will outline how hemophilia exists, reacts, works, and what effects it has on us.
• World Federation of Hemophilia
  • The W F H was created in 1963. Their mission is to promote and advance services and care worldwide to persons with hemophilia and related disorders.
• National Hemophilia Foundation
  • The National Hemophilia Foundation is dedicated to the cures of inherited bleeding disorders and the prevention and treatment of their complications--through education, advocacy, and research.
• Comprehensive Hemophilia Diagnostic and Treatment Center
  • The resources of the U of North Carolina, Chapel Hill.